Autor(en): | Winker, Matteo Stössel, Sandra Neu, Marie Astrid Lehmann, Nadine El Malki, Khalifa Paret, Claudia Joisten, Niklas Bloch, Wilhelm Zimmer, Philipp Faber, Jörg |
Titel: | Exercise reduces systemic immune inflammation index (SII) in childhood cancer patients |
Sprache (ISO): | en |
Zusammenfassung: | While exercise and physical activity have been suggested to reduce mortality and symptoms in cancer, knowledge on these associations in patients with childhood cancer (CCPs) is sparse. Anti-inflammatory properties of exercise might mediate these beneficial effects. We investigated the influence of exercise on the inflammation markers neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and systemic-immune-inflammation index (SII) and associations to patient-reported-outcomes in CCPs in a randomized-controlled trial. Results show associations between inflammation markers and patient-reported outcomes. Compared to the control group, SII was significantly reduced following exercise (p=0.036). Anti-inflammatory effects of exercise are also present in CCPs and may underlie exercise-induced benefits on symptoms. Clinical Trial Registration Number: NCT02612025 |
Schlagwörter: | Tumor entities Cellular inflammation Pediatric oncology Resistance training Endurance training |
Schlagwörter (RSWK): | Kind Onkologie Sport |
URI: | http://hdl.handle.net/2003/40900 http://dx.doi.org/10.17877/DE290R-22756 |
Erscheinungsdatum: | 2021-12-03 |
Rechte (Link): | http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/ |
Enthalten in den Sammlungen: | Institut für Sport und Sportwissenschaft |
Dateien zu dieser Ressource:
Datei | Beschreibung | Größe | Format | |
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Winker2022_Article_ExerciseReducesSystemicImmuneI.pdf | 471.18 kB | Adobe PDF | Öffnen/Anzeigen |
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