Authors: Grühn, Julia
Behr, Alexander S.
Eroglu, Talha H.
Trögel, Valentin
Rosenthal, Katrin
Kockmann, Norbert
Title: From coiled flow inverter to stirred tank reactor – bioprocess development and ontology design
Language (ISO): en
Abstract: Miniaturized bioreactors, such as the coiled flow inverter (CFI), offer several benefits within process development such as lower time and cost factors. In this study, we demonstrate continuous flow experiments in a CFI and transferred them to experiments in a batch reactor by using the oxygen transfer coefficient kLa as a key parameter. In order to simplify the parameter transfer and at the same time develop a basis for future data handling according to the FAIR data principles, an equipment and process ontology was developed for these examples.
Subject Headings: Bioreactor
Coiled flow inverter
2-Phase reaction
Process development
Subject Headings (RSWK): Bioreaktor
Prozessentwicklung <Technik>
Issue Date: 2022-03-29
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