Authors: Hartung, Joachim
Title: An Alternative Method for Meta-Analysis
Language (ISO): en
Abstract: In many fields of applications, test statistics are obtained by combining estimates from several experiments, studies or centres of a multi-centre trial. The commonly used test procedure to judge the evidence of a common overall effect can result in a considerable overestimation of the significance level, leading to a high rate of too liberal decisions. An alternative test statistic is presented and a better approximating test distribution is derived. Explicitely discussed are the methods in the unbalanced heteroscedastic 1-way random ANOVA model and for the probability difference method, including interaction treatment by centres. Numerical results are presented by simulation studies.
Subject Headings: combining experiments
heteroscedastic ANOVA model
interaction treatment by centres
meta-analysis
multi-centre study
probability difference method
random effects
URI: http://hdl.handle.net/2003/4885
http://dx.doi.org/10.17877/DE290R-6916
Issue Date: 1998
Publisher: Universitätsbibliothek Dortmund
Appears in Collections:Sonderforschungsbereich (SFB) 475

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