Authors: Brunnert, Marcus
Müller, Oliver
Urfer, Wolfgang
Title: Genetical and statistical aspects of polymerase chain reactions
Language (ISO): en
Abstract: In this paper we describe the principles of polymerase chain reaction (PCR) and its expanding use in molecular genetic research and molecular medicine. A short introduction of exemplary applications of the PCR is connected with a discussion of the lack of PCR accuracy. We give a statistical model for the PCR and discuss estimation methods in order to quantify the lack of PCR accuracy.
Subject Headings: branching process
estimation of the mutation rate.
lack of PCR accuracy
polymerase chain reaction
Issue Date: 2000
Provenance: Universitätsbibliothek Dortmund
Appears in Collections:Sonderforschungsbereich (SFB) 475

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