|Title:||Genetical and statistical aspects of polymerase chain reactions|
|Abstract:||In this paper we describe the principles of polymerase chain reaction (PCR) and its expanding use in molecular genetic research and molecular medicine. A short introduction of exemplary applications of the PCR is connected with a discussion of the lack of PCR accuracy. We give a statistical model for the PCR and discuss estimation methods in order to quantify the lack of PCR accuracy.|
|Subject Headings:||branching process|
estimation of the mutation rate.
lack of PCR accuracy
polymerase chain reaction
|Appears in Collections:||Sonderforschungsbereich (SFB) 475|
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