Authors: | Brunnert, Marcus Müller, Oliver Urfer, Wolfgang |
Title: | Genetical and statistical aspects of polymerase chain reactions |
Language (ISO): | en |
Abstract: | In this paper we describe the principles of polymerase chain reaction (PCR) and its expanding use in molecular genetic research and molecular medicine. A short introduction of exemplary applications of the PCR is connected with a discussion of the lack of PCR accuracy. We give a statistical model for the PCR and discuss estimation methods in order to quantify the lack of PCR accuracy. |
Subject Headings: | branching process estimation of the mutation rate. lack of PCR accuracy polymerase chain reaction |
URI: | http://hdl.handle.net/2003/5011 http://dx.doi.org/10.17877/DE290R-5381 |
Issue Date: | 2000 |
Provenance: | Universitätsbibliothek Dortmund |
Appears in Collections: | Sonderforschungsbereich (SFB) 475 |
Files in This Item:
File | Description | Size | Format | |
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2000_06.pdf | DNB | 85.83 kB | Adobe PDF | View/Open |
tr06-00.ps | 579.58 kB | Postscript | View/Open |
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