Authors: Hartung, Joachim
Title: A Self-Designing Rule for Clinical Trials with Arbitrary Response Variables
Language (ISO): en
Abstract: For testing one{sided but also two{sided hypotheses concerning several treatment arms in group sequentially performed clinical trials with arbitrary outcome variables, a general learning method is considered that allows for a complete self-designing of the study. All information available prior to a stage is used for estimating the sample size and the weight for the next step. In 'using up' the variance, the test statistic is built in a bounded finite but random number of stages to
Issue Date: 2000
Provenance: Universitätsbibliothek Dortmund
Appears in Collections:Sonderforschungsbereich (SFB) 475

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