Authors: | Hartung, Joachim |
Title: | A Self-Designing Rule for Clinical Trials with Arbitrary Response Variables |
Language (ISO): | en |
Abstract: | For testing one{sided but also two{sided hypotheses concerning several treatment arms in group sequentially performed clinical trials with arbitrary outcome variables, a general learning method is considered that allows for a complete self-designing of the study. All information available prior to a stage is used for estimating the sample size and the weight for the next step. In 'using up' the variance, the test statistic is built in a bounded finite but random number of stages to |
URI: | http://hdl.handle.net/2003/5016 http://dx.doi.org/10.17877/DE290R-5526 |
Issue Date: | 2000 |
Provenance: | Universitätsbibliothek Dortmund |
Appears in Collections: | Sonderforschungsbereich (SFB) 475 |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
2000_11.pdf | DNB | 148.99 kB | Adobe PDF | View/Open |
tr11-00.ps | 134.81 kB | Postscript | View/Open |
This item is protected by original copyright |
This item is protected by original copyright rightsstatements.org