Blood pressure profile in contiuous ambulatory peritoneal dialysis patients

dc.contributor.authorBain, Arba’iyah
dc.contributor.authorCader, Rizna Abdul
dc.contributor.authorGafor, Halim Abdul
dc.contributor.authorIbrahim, Suriani
dc.contributor.authorKong, Norella C.T.
dc.contributor.authorMohd, Rozita
dc.contributor.authorWan Haslina, W.H.
dc.date.accessioned2012-10-11T12:30:35Z
dc.date.available2012-10-11T12:30:35Z
dc.date.issued2012-10-11
dc.description.abstractBackground: Cardiovascular mortality is the leading cause of death in end stage renal disease. Despite being on continuous ambulatory peritoneal dialysis (CAPD), blood pressure (BP) remains poorly controlled. A higher pulse pressure and non dipping are associated with increased cardiovascular mortality. We studied BP control and the prevalence of non dipping in CAPD patients. Methods: All patients undergoing CAPD at our institution who met the inclusion criteria were recruited. We compared BP control and dipping status in diabetic and non diabetic pa-tients on CAPD. We also determined whether BP and peritoneal membrane permeability were associated. Results: Forty six patients with a mean age 45 ± 13 years were enrolled. Diabetic patients were older (mean age 54 ± 13 vs. 40 ± 11 yrs, p <0.001), had a lower mean diastolic BP (80 ± 14 vs. 90 ± 14 mmHg, p = 0.025) and a higher mean pulse pressure (59 ± 17 vs. 49 ± 14 mmHg, p = 0.035). They were also non dippers (n = 15 vs. n = 1, p = 0.007). The low and low average transporters tended to have a higher systolic BP (p = 0.054) and a higher pulse pressure (p = 0.058). On multivariate analysis, age was the main predictor of pulse pressure. Conclusion: Despite being on chronic maintenance PD, BP was not well controlled. Diabetic patients had a higher pulse pressure and were non dippers thereby increasing their cardiovascular risk. We should therefore optimize BP control and aim to restore the nocturnal dip in these patients.en
dc.identifier.issn1611-2156
dc.identifier.urihttp://hdl.handle.net/2003/29665
dc.identifier.urihttp://dx.doi.org/10.17877/DE290R-5607
dc.language.isoende
dc.relation.ispartofseriesEXCLI Journal ; Vol. 11, 2012en
dc.subjectambulatory blood pressure monitoringen
dc.subjectcardiovascular mortalityen
dc.subjectcontinuous ambulatory peritoneal dialysisen
dc.subjectdiabetes mellitusen
dc.subjectdippingen
dc.subjectdiurnal variationen
dc.subjectpulse pressureen
dc.subject.ddc610
dc.titleBlood pressure profile in contiuous ambulatory peritoneal dialysis patientsen
dc.typeTextde
dc.type.publicationtypearticlede
dcterms.accessRightsopen access
eldorado.dnb.zdberstkatid2132560-1

Files

Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Cader_28032012_proof.pdf
Size:
92.06 KB
Format:
Adobe Portable Document Format
Description:
DNB
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.85 KB
Format:
Item-specific license agreed upon to submission
Description: