An overview of platelet indices for evaluating platelet function in children with scorpion envenomation

dc.contributor.authorKonca, Capan
dc.contributor.authorTekin, Mehmet
dc.contributor.authorColak, Pinar
dc.contributor.authorUckardes, Fatih
dc.contributor.authorTurgut, Mehmet
dc.date.accessioned2014-11-25T10:02:19Z
dc.date.available2014-11-25T10:02:19Z
dc.date.issued2014-07-25
dc.description.abstractThe aim of this study was to assess the correlation between platelet indices and scorpion envenomations (SE). Medical records of 76 children who were hospitalised for scorpion stings in the paediatric intensive care unit (PICU) between February 2013 and November 2013, and 55 healthy children who were similar to the patient group in terms of age and sex, were analysed retrospectively. The leucocyte (WBC), thrombocyte (PLT), plateletcrit (PCT), platelet distribution width (PDW) and mean platelet volume (MPV) values of the 76 children with SE were recorded. These values were compared with the healthy control group. Significantly higher WBC and PDW values were noted in patients with SE in comparison to the controls. Patients with SE had significantly lower mean MPV values compared to the healthy controls (9.03 ± 1.26 compared to 10.43 ± 1.44 fL, respectively; p < 0.001). Although the mean platelet count was slightly elevated in the SE group, no statistically significant difference existed between the two groups (p = 0.097). Furthermore, the mean PCT values in the SE group compared to the control group were slightly decreased, but this decrease was not statistically significant (p = 0.141). A significant inverse correlation existed between the MPV values and the WBC (r = -0.450, p < 0.01) and PLT counts (r = -0.420, p < 0.01). The PLT values were significantly correlated with the PCT values (r = 0.687, p < 0.01). This study demonstrated that SE may lead to several alterations in platelet indices. Significantly lower values of MPV and higher values of PDW were detected in SE patients. However, the increase in the platelet counts and the decrease in the PCT values were not significant.en
dc.identifier.issn1611-2156
dc.identifier.urihttp://hdl.handle.net/2003/33697
dc.identifier.urihttp://dx.doi.org/10.17877/DE290R-6928
dc.language.isoen
dc.relation.ispartofseriesEXCLI Journal ; Vol. 13, 2014en
dc.subjectchildrenen
dc.subjectplatelet indicesen
dc.subjectscorpion envenomationen
dc.subject.ddc610
dc.titleAn overview of platelet indices for evaluating platelet function in children with scorpion envenomationen
dc.typeText
dc.type.publicationtypearticle
dcterms.accessRightsopen access
eldorado.dnb.zdberstkatid2132560-1

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