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Case Reports

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http://hdl.handle.net/2003/25617

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  • J. G. Hengstler
    Leibniz Research Centre for Working Environment and Human Factors
    Ardeystr. 67
    D-44139 Dortmund
    Germany
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EXCLI
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Mrs. S. Lindemann
Institute for Occupational Physiology
at the University of Dortmund
Leibniz Research Centre
for Working Environment and Human Factors
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D-44139 Dortmund
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ISSN 1611-2156

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Recent Submissions

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    In silico analysis of terpene synthase genes in Arabidopsis thaliana
    (2007-11-07) Basu, Chhandak; Zwenger, Sam
    Terpenes are defense chemicals found in wide groups of plants. Terpenoids play a large role in plant development and stress response. The terpene synthase family comprises a diverse set of genes, all which contribute to production of terpenoids. We have used tools of bioinformatics and performed an in silico analysis of developmental and tissue specific terpene synthase gene expression in Arabidopsis thaliana, as well as those expressed due to biotic and abiotic environmental stimuli. Using software tools from Genevestigator, a powerful microarray analyzer, we used multiple tool sets to better understand terpene synthase expression in Arabidopsis, which will hopefully open the genetic door to further wet laboratory investigations. The data can be used to predict roles of terpene synthase genes in plant cell division and growth. The data presented here can be used to model for terpene synthesis expression in other plant species and can also be used to integrate basic plant physiology, and ‘omics’ disciplines.
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    Primary biliary cirrhosis associated with rheumatoid arthritis
    (2007-08-17) Fan, Daiming; Han, Ying; Liu, Jingmei; Wang, Jingbo; Yan, Li; Zhou, Xinmin
    Primary biliary cirrhosis(PBC) is a slowly progressive autoimmune disease of the liver which mainly affects women aged between 35 and 45 years.Prolonged liver inflammation can cause scarring, leading to cirrhosis. Although 50 to 60 percent of patients are asymptomatic at diagnosis, they will develop symptoms later. PBC can be associated with arthralgia and other non-hepatic autoimmune diseases, such as Sjögren’s syndrome, sicca syndrome, thyroiditis and scleroderma. PBC and rheumatoid arthritis (RA) have been suggested to coexist in 1.8 to 5.6% of patients with PBC, but data supporting this association are scarce. We report two cases of such an association and discuss how to improve threapy.