Case Reports

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http://hdl.handle.net/2003/25621

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  • J. G. Hengstler
    Leibniz Research Centre for Working Environment and Human Factors
    Ardeystr. 67
    D-44139 Dortmund
    Germany
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Mrs. S. Lindemann
Institute for Occupational Physiology
at the University of Dortmund
Leibniz Research Centre
for Working Environment and Human Factors
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D-44139 Dortmund
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    A case study with breast cancer and brain metastasis encompassing acute onset of amnesia and altered mental status due to limbic encephalitis - biochemical and proteomic aspects
    (2008-05-19) Ghazal, Faten Abou; Haddad, John J.; Hatoum, Hilana; Itani, Osman S.; Mattar, Hanna; Samaha, Ali A.
    A biochemical case study is reported on a 50-year old lady known to have breast cancer. The woman was treated by mastectomy and this was followed by unraveling brain metastases three years post-diagnosis of the cancer, which was treated by radiation and chemotherapy. Two months after ending her treatment, she exhibited acute changes in her mental status manifested by severe amnesia and fever. A generalized analytical and biochemical assessment revealed the presence of paraneoplastic limbic encephalitis.
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    Therapeutic potential of peripheral blood stem cell transplantation in one cirrhotic patient caused by HBV combined with HCV
    (2008-02-08) Fan, Daiming; Han, Huohong; Han, Ying; He, Yuang-long; Liu, Jingmei; Wang, Jianhong; Yan, Li; Zhou, Xinmin
    Stem cell based therapy was very attractive in decompensated liver cirrhosis currently. The possible mechanism might be due to its potential to help tissue regeneration with minimally invasive procedures. Here we report the case of a 44-year-old man, infected by hepatitis B virus (HBV) combined with hepatitis C virus (HCV) for longer than 10 years, who eventually developed decompensated liver cirrhosis. After being infused with mobilized peripheral blood stem cells, the patient showed significantly elevated serum albumin level, cholesterol (CHO), cholinesterase (CHE) and decreased PT (prothrombin time) during the 26 months of follow-up. To our knowledge, this is the first case of transplanting mobilized PBSCs to treat the HBV combined with HCV related decompensated liver cirrhosis.