Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Muñoz‐López, Alvaro | - |
dc.contributor.author | Jung, Anne | - |
dc.contributor.author | Buchmuller, Benjamin | - |
dc.contributor.author | Wolffgramm, Jan | - |
dc.contributor.author | Maurer, Sara | - |
dc.contributor.author | Witte, Anna | - |
dc.contributor.author | Summerer, Daniel | - |
dc.date.accessioned | 2021-05-27T13:46:10Z | - |
dc.date.available | 2021-05-27T13:46:10Z | - |
dc.date.issued | 2020-09-20 | - |
dc.identifier.uri | http://hdl.handle.net/2003/40205 | - |
dc.identifier.uri | http://dx.doi.org/10.17877/DE290R-22078 | - |
dc.description.abstract | Two‐TALE test: Engineered transcription‐activator‐like effector (TALE) repeats can be used to design programmable receptors for improved in situ imaging‐based analysis of 5 mC in user‐defined DNA sequences. Pairs of natural 5 mC‐discriminating and engineered 5 mC‐binding TALEs allow nucleotide resolution analysis of 5 mC with response of both TALEs. This provides an impulse for the design of programmable imaging probes for studying 5 mC functions in chromatin regulation with increased dynamic range. | en |
dc.language.iso | en | de |
dc.relation.ispartofseries | ChemBioChem;Vol. 22. 2021, Issue 4, pp 645-651 | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
dc.subject | DNA methylation | en |
dc.subject | Epigenetics | en |
dc.subject | Imaging probes | en |
dc.subject | Membrane-less organelles | en |
dc.subject.ddc | 570 | - |
dc.subject.ddc | 540 | - |
dc.title | Engineered TALE repeats for enhanced imaging-based analysisof cellular 5-Methylcytosine | en |
dc.type | Text | de |
dc.type.publicationtype | article | de |
dcterms.accessRights | open access | - |
eldorado.secondarypublication | true | de |
eldorado.secondarypublication.primaryidentifier | https://doi.org/10.1002/cbic.202000563 | de |
eldorado.secondarypublication.primarycitation | ChemBioChem. Vol. 22. 2021, Issue 4, pp 645-651 | de |
Appears in Collections: | Chemische Biologie |
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cbic.202000563.pdf | 1.15 MB | Adobe PDF | View/Open |
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