Eldorado: Chemische Biologie

Chemische Biologie : [233]

Light‐activatable MBD‐readers of 5‐methylcytosine reveal domain‐dependent chromatin association kinetics in vivo See

Rho GTPase activity crosstalk mediated by Arhgef11 and Arhgef12 coordinates cell protrusion-retraction cycles See

CRISPR-based screening & functional characterization of long non-coding RNAs in melanoma See

Covalent allosteric inhibitors of Akt generated using a click fragment approach See

Targeting RNA-protein interactions with peptides and small molecule inhibitors See

A bacterial surface display platform for the discovery of cytosine modification readers from cDNA libraries See

Design, synthesis and biological evaluation of tool compounds for the cellular investigation of deubiquitinases See

A cell fusion interaction network during the mating of Saccharomyces cerevisiae See

Transcriptomics-based developmental toxicity and cardiotoxicity assessment using induced pluripotent stem cells See

Targeting of RNA-binding proteins with macrocyclic peptides See

A primer on building life-like systems See

Identification of small molecule inhibitors of the kynurenine pathway See

Discovery of small-molecule modulators of the RNA-binding proteins LIN28 and RNase L See

Structural investigation of cholesterol homeostasis and bacterial toxins See

Probing RNA catalysis in protocellular settings relevant to the origin of life See

Investigation of signal networks that control dynamic cell shape changes See

Imaging-based analysis of 5-methylcytosine at low-repetitive genomic loci using transcription activator-like effector probes See

Modification of peptides for improved membrane permeability and side chain diversity See

Ribozyme activity modulates the physical properties of RNA–peptide coacervates See

Understanding mechanisms of membrane protein Prm1 for membrane fusion during cell-cell fusion of Saccharomyces cerevisiae See