Role of histone modifications in the recruitment of remodeling complex RSC and lysine deacetylase Hst2 to chromatin See

Structural investigations on cholesterol binding membrane proteins SREBP cleavage-activating protein (Scap) and Patched1 by cryo-EM See

Sequence-specific DNA binders for nucleotide resolution analysis genomic 5-methylcytosine by cell imaging See

Kristallisation und strukturbiologische Charakterisierung klinisch-relevanter Mutationsvarianten der Rezeptor-Tyrosinkinasen EGFR und Her2 See

A role of glycerophosphodiesterase EDI3 in glycogen metabolism See

Strukturbiologische Untersuchung und zelluläre Charakterisierung kovalent-allosterischer Akt-Inhibitoren See

Role of WNT1-inducible signaling pathway protein-1 (WISP1) in liver injury See

Identification and characterization of small molecules inducing cellular reactive oxygen species accumulation See

Collective information processing in synthetic morphogenic liposomes and hybrid cell-computer wound healing with optogenetically emulated signaling See

Regulation of natural killer cell cytotoxic pathways during serial killing activity See

Alterations of the glyoxylate metabolism in hepatic steatosis – a risk factor for hyperoxaluria See

Light-Activatable TET-Dioxygenases Reveal Dynamics of 5-Methylcytosine Oxidation and Transcriptome Reorganization See

Click-mediated enrichment of specific genomic loci See

Directed evolution of lysine deacetylases See

Biochemische, kinetische und zelluläre Charakterisierung kovalent-allosterischer Akt-Inhibitoren See

Anwendung der hochaufgelösten bildgebenden MALDI-MS zur Aufklärung der räumlichen Verteilung des Acetaminophens und seiner Biotransformationsprodukte sowie von Taurocholaten in der Leber von Mäusen in Folge einer Acetaminophen Intoxikation See

Designer receptors for nucleotide-resolution analysis of genomic 5-methylcytosine by cellular imaging See

Recursive interaction between encapsulated dynamic microtubule asters and deformable membranes See

Etablierung von biochemischen und strukturbasierten Systemen zur Charakterisierung wirkstoffresistenter EGFR-Mutanten See