Eldorado: Chemische Biologie

Chemische Biologie : [205]

Amphiphile Block-Copolymere und eine Affinitäts-Aufreinigung für die DNA-kodierte Chemie See

Targeting PRMT5 protein-protein interactions with peptidic modulators See

Investigating a role for EDI3 in tumor growth and metastasis in breast cancer using a doxycycline-inducible knockdown system See

Differentiation of distinct mesoderm subtypes from regulatory interactions between FGF and BMP signaling See

Structural insights into muscle organisation by electron cryo-tomography See

Recursion quantification analysis reveals a cellular morphodynamics - ERK activity recursive relationship See

Structural basis for specific inhibition of the deubiquitinase UCHL1 See

Reconstitution of RhoGTPase membrane loading See

Optochemical control of DNA methylation erasers and readers enables kinetic insights into their domain-dependent interplay See

Stem cell-based phenotypic screening and characterization of novel BMP mimetics See

Molecular insights into Bacillus anthracis anthrax lethal complex See

Application of the cell painting assay for pseudo-natural product projects See

Design and synthesis of Nrf2-derived hydrocarbon stapled peptides for the disruption of protein-DNA-interactions See

Design, Synthese und Evaluation Mutanten-selektiver Inhibitoren zur Adressierung onkogener KRas-Varianten See

Development of methods toward the synthesis of novel bioactive natural product-like scaffolds See

Programmable protein-DNA crosslinking for the direct capture and quantification of 5-formylcytosine See

Epigenetic chromatin modification by amber suppression technology See

Light-activatable TET-dioxygenases reveal dynamics of 5-Methylcytosine oxidation and transcriptome reorganization See

Identification and characterization of inhibitors of hedgehog-induced osteoblast differentiation See